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Keycap Digit One

Theme D - Continuity & Change

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Direct Hit

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Hey future biologists! 🌟 Ready to dive into the world of tiny, invisible tags that have HUGE impacts on your genes? Yep, we&#39;re talking about epigenetic tags today. Plus, I&#39;ll spill the tea ☕ on how to boost your internet search game. So, let&#39;s get started!

Definition

<ul>
	<li>DNA Methylation: The process of replacing a hydrogen atom in a DNA base with a methyl group (-CH3).</li>
</ul>

Fun Fact 🎉

Think of it like putting a &quot;Do Not Disturb&quot; sign on your bedroom door. You&#39;re not changing the room; you&#39;re just telling people to stay out.

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Key Concepts

<ul>
	<li>Targets: Mainly affects cytosine but can also target adenine.</li>
	<li>Epigenetic Tag: The methyl group is an example of an &quot;epigenetic tag.&quot;</li>
	<li>Promoter: A sequence near the gene that acts as a landing pad for RNA polymerase (a crucial enzyme for gene expression).</li>
</ul>

Real-World Impact 🌍&nbsp;DNA Methylation is like a &quot;volume knob&quot; for genes. Too much methylation (think of it as turning the volume way down) can lead to diseases like cancer.

Definition

<ul>
	<li>Nucleosome: DNA is wound around eight histone proteins.</li>
	<li>Histone Tails: The long tails of histones sticking out of the nucleosome.</li>
</ul>

Fun Fact 🎉

Think of histones like the spool around which you&#39;d wind up your headphone wires (if you still use wired headphones, that is).

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Key Concepts

<ul>
	<li>Histone Modification: Adding groups like methyl, acetyl, or phosphate to the tails.</li>
	<li>Epigenetic Tags: These added groups are another type of epigenetic tag.</li>
	<li>Regulation: Modifies accessibility to transcription factors, which are the &quot;traffic controllers&quot; for gene expression.</li>
</ul>

Real-World Impact 🌍

Imagine you&#39;re a rockstar (🎸), and your histones are your guitar&#39;s tuning pegs. Twist them one way, and the sound is perfect. Twist them another, and you&#39;re out of tune&mdash;same with genes!

Searching for Files

<ul>
	<li>For a .pdb file of a nucleosome, search: <code>file type:pdb nucleosome</code></li>
	<li>For a .pdf, search: <code>file type:.pdf nucleosome</code></li>
</ul>

Site Filtering

<ul>
	<li>Use site:edu genetic testing for academic info.</li>
	<li>Just genetic testing will give you a broader, but more commercial, set of results.</li>
</ul>

Real-World Impact 🌍

Imagine you&#39;re a detective 🕵️&zwj;♀️ and the internet is your crime scene. Would you rather sift through a dumpster for clues or go straight to the file cabinet with all the evidence? Yep, learning these tricks is like finding that file cabinet!

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There you have it, folks! Now, you&#39;re ready to dazzle your biology teacher and level up your web searching. Keep being awesome! 🌟

Unlock Epigenetic Tags: DNA & Histone Methylation Explained!

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Higher Level

Biology HL

Theme D - Continuity & Change

Unlock Epigenetic Tags: DNA & Histone Methylation Explained!

Table of content

Introduction

Epigenetics - DNA Methylation

Unlock the Full Content!

Theme D - Continuity & Change

Unlock Epigenetic Tags: DNA & Histone Methylation Explained!

Table of content

Introduction

Epigenetics - DNA Methylation

Unlock the Full Content!