Hey future biologists! 🦠 Ready to dive into the exciting world of sex-linked genetic disorders? Today, we're focusing on haemophilia as our star example. This is not just textbook stuff; it's real, it affects people, and understanding it could make you the superhero of the genetic world! 🦸‍♀️🦸‍♂️

Sex-Linked Genetic Disorders: These are disorders you inherit based on your sex chromosomes (X & Y). Spoiler alert: Most of these disorders are due to recessive alleles of genes!

X and Y Chromosomes: X has the spotlight here; Y is like the shy guy in the corner. That’s because the X chromosome carries many more genes than the Y chromosome.

Males Vs. Females: Males are more likely to have these disorders because they only have one X chromosome. If that X has the bad gene, oops, they're affected. Females have two X chromosomes, so they have a backup!

Haemophilia: Our celeb disorder for today. It's primarily a guy issue and messes with blood clotting due to a lack or faulty form of a protein called Factor VIII.

Treatment: Don’t lose hope; it’s treatable by infusing Factor VIII from donor blood!

Frequency: In boys, it’s like 1 in 10,000. In girls, it’s astronomically rare—like finding a unicorn! 🦄

👨‍🔬 What are Sex-Linked Genetic Disorders?

• 📌 Definition: Disorders that occur due to genes on the sex chromosomes.
• 💡 Real-world example: Think of genes like apps on your phone. Some apps (genes) are exclusive to specific models (chromosomes). Imagine you got a faulty app that only runs on iPhones (X chromosome). Android users (girls with another X as a backup) wouldn't be affected!

• 📌 X has More Genes: The X chromosome is like the "Swiss Army knife" of chromosomes—it's got everything! Y is more like a single screwdriver.
• 💡 Real-world example: Picture a huge shopping mall (X chromosome) full of shops (genes) versus a tiny convenience store (Y chromosome).