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Direct Hit

Theme A - Unity & diversity

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Page Facing Up

Theme B - Form & Function

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Pill

Theme C - Interaction &  Interdependence

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Keycap Digit One

Theme D - Continuity & Change

Hey Biology Superstar! Ready to dive into the world of nucleosomes? Picture it like a DNA party with the coolest dance move ever! 🧬✨

Imagine your DNA looking like a string of beads. Each bead is a nucleosome, making it the party room for DNA!

<ul>
	<li>The Core: It&#39;s made of eight histone proteins (2 copies of 4 different types). They form a disc-shaped structure.</li>
	<li>The DNA Twist: DNA wraps around the core twice, like twirling a ribbon around a maypole.</li>
	<li>Guest DJ, Histone H1: This additional histone helps bind the DNA to the core and packages chromosomes for division.</li>
	<li>Linker DNA: Think of it as the corridor between adjacent dance floors (nucleosomes).</li>
</ul>

<ul>
	<li>Eukaryotes (Plants, Animals, etc.): Yes! 🎉</li>
	<li>Bacteria: No! 😢 (Their DNA is &quot;naked&quot; because it doesn&#39;t associate with histones.)</li>
</ul>

Want to see nucleosomes in 3D? Follow these steps:

<ul>
	<li>Visit: <a href="http://www.rcsb.org/" target="_new">www.rcsb.org</a>, search for &quot;human nucleosome structure.&quot;</li>
	<li>Click: &quot;3D View&quot; to enter the 3D world of nucleosomes.</li>
	<li>Rotate: See the two copies of each histone protein. They&#39;re like tails extending from the core.</li>
	<li>Observe: Approximately 150 base pairs (bp) of DNA wrapped nearly twice around the core. It&#39;s a tight hug!</li>
	<li>N-Terminal Tail: Check the tail projecting from each histone core. They are fashion accessories that can change to regulate gene expression.</li>
	<li>Positively Charged Amino Acids: They&#39;re like magnets for the negatively charged DNA. Imagine your socks sticking to a balloon after rubbing it on your hair - that&#39;s how these amino acids stick to the DNA!</li>
</ul>

Real-World Example: Ever wonder why you can fit so much data into a tiny USB drive? Well, DNA packaging is somewhat similar. Wrapping DNA around histones helps in compacting a massive amount of genetic information into the tiny space of a cell nucleus.

Nucleosomes are a masterpiece of biological architecture. They not only help in the packaging of DNA but also play a vital role in gene regulation. So, next time you dance, remember the nucleosomes and their endless twirls!

Happy Studying! 🎓🧪🔬

Theme A - Unity & diversity

Unlock Nucleosome Secrets: Visualize DNA Structure!

Table of content

Nucleosome - the DNA dance floor 🕺💃

What's a nucleosome?

Party components

Unlock the Full Content!

Theme A - Unity & diversity

Unlock Nucleosome Secrets: Visualize DNA Structure!

Table of content

Nucleosome - the DNA dance floor 🕺💃

What's a nucleosome?

Party components

Unlock the Full Content!